Platelet-rich fibrin (PRF) is a by-product of blood (plasma) that is rich in platelets. Until now, its use has been confined to the hospital setting. This was due mainly to the cost of separating the platelets from the blood and a large amount of blood needed to produce a suitable quantity of platelets. New technology permits doctors to harvest and produces a sufficient quantity of platelets from only 10 ccs of blood, which is drawn from the patient while they are having outpatient surgery PRF permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cells and cell-types to the wound in order to initiate the healing process. One of those cell types is platelets. Platelets perform many functions, including the formation of a blood clot and release of growth factors (GF) into the wound. These growth factors; platelet-derived growth factors (PDGF), transforming growth factor beta (TGF), and insulin-like growth factor (ILGF), function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue. The more growth factors released and sequestered into the wound, the more stem cells are stimulated to produce new tissue. Thus, PRF permits the body to heal faster and more efficiently. A subfamily of TGF, is bone morphogenic protein (BMP). BMP has been shown to induce the formation of new bone in research studies in both animals and humans.
What is L-PRF?
L-PRF stands for Leukocyte – Platelet Rich Fibrin. Leukocytes are also known as white blood cells. They are part of the immune system and are responsible for helping heal our bodies. Platelets are also blood cells. They are responsible for attracting healing cells, creating blood clots. They are also key cells for producing growth factors. Fibrin is another component of the blood that works with platelets to create blood clots.
How are L-PRF clots created?
L-PRF clots are first created by taking a small blood sample from you. The blood sample tubes are spun according to a specific process. This creates a matrix or blood clot. The matrix is then removed from the tube and placed in a device designed to compress the matrix to the desired thickness.
What is Platelet Fibrin Therapy?
Platelet Fibrin Therapy uses L-PRF clots to promoting healing.
Is L-PRF painful?
It is as painless as a routine blood draw.
How does L-PRF work to heal?
L-PRF provides a concentrated release of healing proteins, creates a scaffolding to help direct healing and also forms a more efficient network for cells to communicate with other cells and tissues. Due to the high concentration of platelets and leukocytes within the L-PRF clot, the fibrin releases growth factors for up to14 days after placement. This is when the body is repairing itself and needs the extra help to heal.
Are there any side effects or complications from L-PRF?
L-PRF uses your own blood, with NO additive whatsoever. Reducing the risk of allergy, or side effects because your own concentrated platelets, with their own unique healing abilities, are simply re-introduced at the site of your extraction, implant placement or another surgical site.
What types of conditions are treated with L-PRF?
Currently, L-PRF is being used for dental and oral maxillofacial surgical procedures, including dental implants, bone defects, extraction sockets, sinus and dental ridge augmentation, palatal defects, and maxillary bone atrophy. • All natural, 100% you • Simple holistic procedure • Latest healing technology • No chemicals, foreign substances or additives – just you • FDA cleared medical device extraction sockets, sinus and dental ridge augmentation, palatal defects, and maxillary bone atrophy.
Ask us how L-PRF can benefit you at our practice with Endodontic Microsurgery!